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Cholecystokinin Octapeptide, [125I]-, Bolton-Hunter Labeled, 10µCi

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2023-10-20
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珀金埃尔默企业管理(上海)有限公

高级会员6生产厂家

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分析仪器:原子光谱,分子光谱,色谱,质谱等
产品简介
Cholecystokinin Octapeptide (CCK-8), labeled with 125I. Cholecystokinin is a neuropeptide that exists in several forms, identified by the number of amino acids in the peptide sequence. CCK8 contains 8......
详细信息

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX203:

  1. Kopin, A.S., McBride, E.W., Chen, C., Freidinger, R.M., Chen, D., Zhao, C.M., Beinborn, M. (2003), Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation. PNAS, 100 (9): 5525-5530.
  2. Kopin, A.S., Lee, Y.M., McBride, E.W., Miller, L.J., Lu, M., Lin, H.Y., Kolakowski, L.F. Jr, Beinborn, M. (1992), Expression cloning and characterization of the canine parietal cell gastrin receptor. PNAS, 89 (8): 3605-3609.

规格

检测方法 Radiometric
新鲜的很多天 First Monday of each month
标签位置 Nominally Labeled
产品品牌名称 NEN Radiolabeled Ligands
放射性同位素 I-125
放射性核素 125I
受体类型 Cholecystokinin
运输条件 干冰
特殊订购信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
治疗领域 CNS & Neurologic, Inflammation, Gastrointestinal
产品尺寸 10 µCi
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