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Kainic acid, [Isopropenyl-3H]-, 250µCi (9.25MBq)

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2023-10-20
型号
珀金埃尔默企业管理(上海)有限公

高级会员6生产厂家

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分析仪器:原子光谱,分子光谱,色谱,质谱等
产品简介
Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
详细信息

Kainic acid (kainate), labeled with tritium (3H) on the isoprenyl group. Kainic acid is a selective agonist for kainate glutamate receptors, which play a role synaptic plasticity. It is a glutamate analog. Common applications include ligand binding assays.

This product replaces NET875001MC.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET1232:

  1. Honoré T, Davies SN, Drejer J, Fletcher EJ, Jacobsen P, Lodge D, Nielsen FE. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science (1988) 241 (4866): 701-703.

规格

分子量 213.2
放射性同位素 H-3
放射性核素 3H
运输条件 蓝冰
特殊订购信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
产品尺寸 250 µCi
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