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中性树胶使用说明书

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中性树胶使用说明书分子生物学领域：
涉及核酸纯化、常用分子生物学试剂、PCR等相关试剂盒。
分子生物学试剂：拥有的价格优势，品质可信赖，市场占比庞大。
752-64-9    20mg    Mesaconitine 新
19685-10-0    20mg    9-Methoxycamptothecin 9-甲氧基喜树碱
484-20-8    20mg    5-Methoxypsoralen 佛手柑内酯
298-81-7    20mg    8-Methoxypsoralen 花椒毒素
11013-97-1    20mg    Methyl hesperidin 甲基橙皮苷
54522-52-0    20mg    Methyl protodioscin 甲基原薯蓣皂苷
88901-36-4    20mg    Mogroside Ⅴ 罗汉果皂苷Ⅴ
96990-18-0    20mg    Momordin Ic 地肤子皂苷Ic
643-84-5    1mg    Malvinidol Chloride 氯化锦葵素
5945-50-6    10mg    Monotropein 水晶兰苷
480-16-0    20mg    Morin hydrate 桑色素
25406-64-8    20mg    Morroniside 莫诺苷
102841-42-9    20mg    Mulberroside A 桑皮苷A
541-91-3    0.15mL    Muscone 麝香酮
529-44-2    20mg    Myricetin 杨梅素

and Ser-392; was initially thought to be mediated by STK11/LKB1 but it was later shown that it is indirect and that STK11/LKB1-dependent phosphorylation is probably mediated by downstream NUAK1 (PubMed:21317932). It is unclear whether AMP directly mediates phosphorylation at Ser-15. Phosphorylated on Thr-18 by isoform 1 and isoform 2 of VRK2. Phosphorylation on Thr-18 by isoform 2 of VRK2 results in a reduction in ubiquitination by MDM2 and an increase in acetylation by EP300. Stabilized by CDK5-mediated phosphorylation in response to genotoxic and oxidative stresses at Ser-15, Ser-33 and Ser-46, leading to accumulation of p53/TP53, particularly in the nucleus, thus inducing the transactivation of p53/TP53 target genes. Phosphorylated at Ser-315 and Ser-392 by CDK2 in response to DNA-damage. 
Dephosphorylated by PP2A-PPP2R5C holoenzyme at Thr-55. SV40 small T antigen inhibits the dephosphorylation by the AC form of PP2A. 
May be O-glycosylated in the C-terminal basic region. Studied in EB-1 cell line. 
Ubiquitinated by MDM2 and SYVN1, which leads to proteasomal degradation. Ubiquitinated by RFWD3, which works in cooperation with MDM2 and may catalyze the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. Ubiquitinated by MKRN1 at Lys-291 and Lys-292, which leads to proteasomal degradation. Deubiquitinated by USP10, leading to its stabilization. Ubiquitinated by TRIM24, which leads to proteasomal degradation. Ubiquitination by TOPORS induces degradation. Deubiquitination by USP7, leading to stabilization. Isoform 4 is monoubiquitinated in an MDM2-independent manner. 
Monomethylated at Lys-372 by SETD7, leading to stabilization and increased 中性树胶使用说明书transcriptional activation. Monomethylated at Lys-370 by SMYD2, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity. Lys-372 monomethylation prevents interaction with SMYD2 and subsequent monomethylation at Lys-370. Dimethylated at Lys-373 by EHMT1 and