服务承诺：工作时间内提供免费的技术咨询和指导 。我公司的技术人员都经过专业培训的，将为您提供满意的产品和真诚的服务。
核固红号：6409-77-4   
英文名称：Nuclear fast red；Calcin red；Kernechtrot；1-Amino-2,4-dihydroxyanthraquinone-3-sulfonic acid sodium salt ；C.I. 60760   
其他名称：细胞核坚牢红；钙红；核快红；乙二醛缩双邻氮基酚   
号：6409-77-4   
C14H8NNaO7S=357.27   
级别：FMP   
分光有效含量：≥90.0   
层析试验：合格   
薄层层析试验：合格   
干燥失量：≤5.0%   
性状(以下信息仅供参考)：微红至深棕色粉末。遇氢氧化钠成浅紫色，在硫酸中为棕色溶液。溶于乙醇和水。Z大吸收波长518nm。有刺激性。文献上也有指本品为中性红(Neutral red)的   
用途：本品仅供科研，不得用于其它用途。(以下用途仅供参考)结缔组织细胞核染色。测定钙的试剂   
保存：RT，避光 客户根据核固红号：6409-77-4性质、化学式、分子式、结构式、比重、密度、号、沸点、熔点、水溶性、MSDS、用途、作用、规格包装、性状、注意事项、英文名、别称、纯度、级别等情况，本产品化学性质稳定，运输条件不苛刻，一般储存在阴凉，干燥，通风良好的地方，远离不相容的物质。保持容器密闭。
试剂品牌：TCI、sigma、Alfa、Avocado、Aldrich、ACROS、Fluka、ICN（MP）等
包装：1kg、100g、10g、250g、25g、500g、50g、5g等包装
级别：GR级别、AR级别、CP级别、L.P.级别等
公司提供的核固红号：6409-77-4*，货源充足。严格的生产质量控制体系，包括：优级纯，分析纯，化学纯，试剂级，基准试剂，实验纯，教学试剂，高纯试剂，色谱纯，光谱纯，电子纯。各种包装规格，并可提供包装定制，咨询订购。

购买须知：
【价格方面】   
    每个时期原料的价格都会波动，产品的价格会有所升降，以上报价仅为参考报价！咨询选购！

 【付款方式】 
    现金，支付宝，银行转帐，汇款，支票，本票；
    请将款项汇至我司公司账户（开票的）或者老板的私人账户上面，接受支付宝付款； 
    我司收到款项后会根据客户的相关要求尽快安排发货！

    【发货时间】 
     物流基本上在下午2点之前提交确认的订单，都将尽力安排当天发货； 
    如果订单产品需要拆分及其他特殊情况的要求，则可能会有一定的延时。

    【配送方式】 
    确定的订单后，小货我司将通过顺丰、韵达等快递送达； 
    大量货物会更具情况以德邦、远成，普华，中铁等物流的运输方式发货。

    【其他服务】 
    如您对产品特性及技术指标有特殊要求，我公司可以提供质检单和相关产品的资料和文件； 
    如果对产品的包装或者分装的有要求的话，也请及时通知我方，我方好根据要求尽量满足您的所需求。

    【服务宗旨】 
    竭诚提供优质产品，售后服务客户满意度100％

Isoform e3C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Subunit : Homodimer. Interacts with NOSIP and NOSTRIN.
Subcellular Location : Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Tissue Specificity : Plaets, placenta, liver and kidney.
Post-translational modifications : Phosphorylation by AMPK at Ser-1177 in the presence of Ca(2+)-calmodulin (CaM) activates activity. In absence of Ca(2+)-calmodulin, AMPK also phosphorylates Thr-495, resulting in inhibition of activity. Phosphorylation of Ser-114 by CDK5 reduces activity.
Similarity : Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
Database links : UniProtKB/Swiss-Prot: P29474.3 human
UniProtKB/Swiss-Prot: Q62600.4 rat
UniProtKB/Swiss-Prot: P70313.4 mouse
英文名称  Anti-NGFR/p75NTR
中文名称  神经生长因子受体抗体
别    名  Gp80 LNGFR; ngfrp75; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; NGF receptor; p75 ICD; CD271; CD271 antigen; Gp80 LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor; Nerve growth factor receptor TNFR superfamily member 16; NGF receptor; NGFR; p75 ICD; p75 Neurotrophin receptor; p75 NTR; TNFR Superfamily Member 16; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; TNR16_HUMAN.
浓    度  1mg/1ml
规 格  0.2ml/200μg
抗体来源  Rabbit 
克隆类型  polyclonal
交叉反应  Human, Mouse, Rat, Dog 
产品类型  一抗   
研究领域  细胞生物 神经生物学 信号转导 
蛋白分子量  predicted molecular weight: 42kDa
性    状  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NGFR/p75NTR
亚    型  IgG
纯化方法  affinity purified by Protein A
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500
（石蜡切片需做抗原修复）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The low affinity NGFR (Nerve growth factor receptor) is a 75kDa membrane-spanning glycoprotein lacking intrinsic tyrosine kinase activity. p75NGFR interacts with TrkA, the high affinity NGF receptor and potentiates TrkA signaling at low NGF concentrations. The p75 receptor binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NGFR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective cellular populations to programmed cell death. It is expressed on many neuronal cells types including many embryonic forms and the receptor can be used to isolate neuronal progenitor cells. NGF is important for the development, differentiation and survival of a variety of neuronal and non-neuronal cells. Its action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75. p75NGFR binds neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5, and NT-6. p75NGFR belongs to the TNF-R superfamily and is reported to mediate NGF-induced apoptosis.
Function : Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.