表皮生长因子，SIGMA E4127-5×0.1MG，来源于小鼠颌下腺

分类 抗体

级别 优级纯GR

产品规格 SIGMA E4127-5×0.1MG

CAS 62229-50-9

品牌 Sigma

用途范围 生物科研

保存温度 2-8℃

英文名称 Epidermal Growth Factor from murine submaxillary g

供应商      上海研伴实业有限公司

表皮生长因子 来源于小鼠颌下腺         SIGMA E4127-5×0.1MG

suitable for cell culture

· 产品编号：E4127

· 中文名称：表皮生长因子 来源于小鼠颌下腺

· 英文名称：Epidermal Growth Factor from murine submaxillary gland

· 英文别名:EGF Epidermal cell growth factor

· CAS号：62229-50-9

· 保存温度：2-8 °C

· EC号：263-468-7

· MDL号：MFCD01634807

订货信息：

产品规格价格(RMB)

· E4127-0.1MG1,838.07元

· E4127-5X0.1MG7,376.85元

注：此价格仅供参考，请以SIGMA价格为准，优惠价请电询。

性能描述

Analysis Note

The biological activity is measured in a proliferation assay using BALB/MK cells.

Biochem/physiol Actions

Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.

Preparation Note

Purified by gel filtration.

Physical form

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

General description

Epidermal Growth Factor (EGF) is a 6 kDa polypeptide discovered by Cohen and Levi -Montalcini and isolated from mouse submaxillary glands. EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa and SV40-3T3 cells. In tissue cultures EGF can act to reduce or eliminate the requirement for serum and is often used in conjunction with other media additives and hormones, such as Insulin (Product No. I1882), Transferrin (Product No. T 5391), and Prostaglandin E1 (Product No. P7527). Cellular metabolic effects of EGF include stimulation of ion fluxes, glucose transport, glycolysis, and synthesis of DNA, RNA and proteins.

Human EGF was originally isolated from human urine as β-Urogastrone, an inhibitor of gastric acid secretion. Mouse and human EGF are 70% homologous in their sequence of 53 amino acids, act upon the same EGF receptor, elicit nearly identical biological effects and are highly inter-species cross-reactive.

EGF is structurally homologous to human Transforming Growth Factor-α (Product Nos. T7533 and T2035), which exerts its actions through EGF receptors. EGF is also homologous to a sequence contained in a 19 kDa protein of Vaccinia virus, which appears to utilize the EGF receptor to gain entry into cells. The EGF receptor is a 170 kDa glycoprotein having EGF-activated protein tyrosine kinase activity. Plaet-Derived Growth Factor(PDGF, Product No. P8147) transmodulates the EGF receptor by reduc ing both its EGF affinity and its kinase activity.

性质

表皮生长因子，SIGMA E4127-5×0.1MG，来源于小鼠颌下腺其他相关产品目录：

JW.HU1001 Human (TCR) ELISA kits 48T/96T 国产/进口

JW.HU1002 Human 1,3-DPG ELISA kits 48T/96T 国产/进口

JW.HU1003 Human 1,3-βD-Glu ELISA kits 48T/96T 国产/进口

JW.HU1004 Human 1,5-AG ELISA kits 48T/96T 国产/进口

JW.HU1005 Human 11-DH-TXB2 ELISA kits 48T/96T 国产/进口

JW.HU1006 Human 12-HETE ELISA kits 48T/96T 国产/进口

JW.HU1007 Human 15-LO/LOX ELISA kits 48T/96T 国产/进口

JW.HU1008 Human 16-α OHE-1 ELISA kits 48T/96T 国产/进口

JW.HU1009 Human 17-KS ELISA kits 48T/96T 国产/进口

JW.HU1010 Human 17-OHCS ELISA kits 48T/96T 国产/进口

JW.HU1011 Human 17-OHP ELISA kits 48T/96T 国产/进口

JW.HU1012 Human 2,3-dinor-TXB2 ELISA kits 48T/96T 国产/进口

JW.HU1013 Human 2，3-DPG ELISA kits 48T/96T 国产/进口

JW.HU1014 Human 26S PSM ELISA kits 48T/96T 国产/进口

JW.HU1015 Human 28S rRNP ELISA kits 48T/96T 国产/进口

JW.HU1016 Human 3-NT ELISA kits 48T/96T 国产/进口

JW.HU1017 Human 5-HIAA ELISA kits 48T/96T 国产/进口

JW.HU1018 Human 5-HT ELISA kits 48T/96T 国产/进口

JW.HU1019 Human 5-LO/LOX ELISA kits 48T/96T 国产/进口

JW.HU1020 Human 5-NT ELISA kits 48T/96T 国产/进口

JW.HU1021 Human 6-keto-PGF1a ELISA kits 48T/96T 国产/进口

JW.HU1022 Human 6-K-PG ELISA kits 48T/96T 国产/进口

JW.HU1023 Human 6-OHDA ELISA kits 48T/96T 国产/进口

JW.HU1024 Human 8-epi-PGF2α ELISA kits 48T/96T 国产/进口

JW.HU1025 Human 8-OHdG ELISA kits 48T/96T 国产/进口

JW.HU1026 Human ⅠCTP ELISA kits 48T/96T 国产/进口

JW.HU1027 Human Ⅷ-Ag ELISA kits 48T/96T 国产/进口

JW.HU1028 Human AA ELISA kits 48T/96T 国产/进口

JW.HU1029 Human AAA ELISA kits 48T/96T 国产/进口

JW.HU1030 Human AACT ELISA kits 48T/96T 国产/进口

JW.HU1031 Human AAV ELISA kits 48T/96T 国产/进口

JW.HU1032 Human ABCA1 ELISA kits 48T/96T 国产/进口

JW.HU1033 Human ABCG2 ELISA kits 48T/96T 国产/进口

JW.HU1034 Human ABM-Ab ELISA kits 48T/96T 国产/进口

JW.HU1035 Human ABP ELISA kits 48T/96T 国产/进口

JW.HU1036 Human AC-1 ELISA kits 48T/96T 国产/进口

JW.HU1037 Human ACA ELISA kits 48T/96T 国产/进口

JW.HU1038 Human ACA/CENP ELISA kits 48T/96T 国产/进口

JW.HU1039 Human ACA-IgA ELISA kits 48T/96T 国产/进口

JW.HU1040 Human ACA-IgG ELISA kits 48T/96T 国产/进口

JW.HU1041 Human ACA-IgM ELISA kits 48T/96T 国产/进口

JW.HU1042 Human ACAST-DⅣ ELISA kits 48T/96T 国产/进口

JW.HU1043 Human ACE ELISA kits 48T/96T 国产/进口

JW.HU1044 Human ACEⅠ ELISA kits 48T/96T 国产/进口

JW.HU1045 Human ACH ELISA kits 48T/96T 国产/进口

JW.HU1046 Human AChE ELISA kits 48T/96T 国产/进口

JW.HU1047 Human AChRab ELISA kits 48T/96T 国产/进口

JW.HU1048 Human ACO-2 ELISA kits 48T/96T 国产/进口

JW.HU1049 Human ACP ELISA kits 48T/96T 国产/进口

JW.HU1050 Human AcSDKP ELISA kits 48T/96T 国产/进口

表皮生长因子，SIGMA E4127-5×0.1MG，来源于小鼠颌下腺