Anti-5-HTR3抗体,5-羟色胺受体3抗体产品介绍产品详细资料

产品编号 BYK-2126R

性    状 Lyophilized or Liquid
浓    度 1mg/1ml
亚    型 IgG
纯化方法 affinity purified by Protein G

英文名称 5-HTR3
中文名称 5-羟色胺受体3抗体
别    名 5 HT 3; 5 HT3; 5 HT3A; HTR-3A; 5 HT3A receptor; 5 HT3R; 5 HT3RA; 5 hydroxytryptamine (serotonin) receptor 3A; 5 Hydroxytryptamine receptor 3; 5-HT-3; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT 3; 5HT 3A; 5HT receptor; 5HT3 serotonin receptor; 5HT3A_HUMAN; 5HT3R; HTR 3; HTR3; Htr3a; Serotonin gated ion channel receptor; Serotonin receptor 3; Serotonin receptor 3A; Serotonin-gated ion channel receptor 3a; 5HT3A_HUMAN. 
研究领域 神经生物学  通道蛋白  细胞膜受体  
分 子 量 53kDa
细胞定位 细胞膜 

抗体来源 Mouse or Rabbit
克隆类型 Monoclonal or Polyclonal
产品应用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此产品应用不做依据，具体产品应用与实验稀释比请！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-5-HTR3抗体,5-羟色胺受体3抗体产品介绍产品介绍 

      The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family.

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.

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