Anti-IL12/FITC科研抗体产品

From：Abcam

Catalog Number : BYK- 0767R-FITC      
Quantity size :   100ug (2mg/1ml, Lyophilized or Liquid. Buffer = 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide. Reconstitute with 50ul sterile distilled water.)

Background:  IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

Also known as:  IL12; IL-12; CLMF p35; CLMF1; CTL maturation factor (TcMF); Cytotoxic lymphocyte maturation factor 1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL 12 subunit p35; IL12A; Interleukin 12 alpha chain; Interleukin 12 p35; Interleukin 12A; Natural killer cell stimulatory factor 1; NK cell stimulatory factor chain 1; NKSF1; p35; IL12A_MOUSE.

Specificity:   -Rabbit Polyclonal IgG, affinity purified by Protein A.

-FITC conjugated

-Reacts with: Mouse, Rat,

-Immunogen:KLH conjugated synthetic peptide derived from mouse IL-12.

-Predicted molecular weight: 22kDa

Application:    IF=1:50-200  Flow-Cyt=1:50-200

              Excitation spectrum: 490-495nm

              Emission spectrum: 520-530nm

              Not yet tested in other applications.

              Optimal working dilutions must be determined by the end user.

Storage:      Store at -20 °C for one year. Avoid repeated freeze/thaw

             cycles. The Lyophilized or Liquid antibody is stable at room

             temperature for at least one month and for greater than a year when

             kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or

             diluent of antibody the antibody is stable for at least two weeks at

             2-4 °C.

Important Note: This product as supplied is intended for research

              use only, not for use in human, therapeutic or diagnostic

              applications..